Hey there @Moroccokid, welcome to our Community!
If your hard drive is running out of space and you want to remove some folders from your Dropbox folder on your computer but not your Dropbox account, you can selectively sync them.
Please bear in mind that you can remove or keep just entire folders. So, what you can do is you can save this particular file in a separate folder, and choose to sync just this one.
I hope this helps, but don't hesitate to get back to me if you have any other questions!