I can't start the desktop app on Windows as I'm getting a permissions error

I've been using Dropbox installed on my Windows 11 for few months.  While using computer, it gave me a popup about permission and the process ended. A reboot now gives me an error "Couldn't start Dropbox" with the full log below.

I didn't change any permissions, didn't install any new software.

What happened?    Looks like permission error somehow.   Thank you!

bn.BUILD_KEY: Dropbox
bn.VERSION: 193.4.5594
bn.constants.WINDOWS_SHELL_EXT_VERSION: 69
bn.is_frozen: True
machine_id: 091c223e-1dd3-499e-a310-642ffeba31d9
pid: 15876
cwd: 'C:\\WINDOWS\\SysWOW64'
     real_path='C:\\Windows\\SysWOW64'
           	mode=0o40777	uid=0	gid=0
     parent	mode=0o40777	uid=0	gid=0
HOME: None
appdata: 'C:\\Users\\larry\\AppData\\Local\\Dropbox\\instance1'
         real_path='C:\\Users\\larry\\AppData\\Local\\Dropbox\\instance1'
               	mode=0o40777	uid=0	gid=0
         parent	mode=0o40777	uid=0	gid=0
dropbox_path: 'C:\\Users\\larry\\Dropbox'
              real_path='C:\\Users\\larry\\Dropbox'
                    	mode=0o40555	uid=0	gid=0
              parent	mode=0o40777	uid=0	gid=0
sys_executable: 'C:\\Program Files (x86)\\Dropbox\\Client\\Dropbox.exe'
                real_path='C:\\Program Files (x86)\\Dropbox\\Client\\Dropbox.exe'
                      	mode=0o100777	uid=0	gid=0
                parent	mode=0o40777	uid=0	gid=0
trace.__file__: 'C:\\Program Files (x86)\\Dropbox\\Client\\193.4.5594\\python-packages.zip\\dropbox\\client\\ui\\common\\boot_error.pyc'
                real_path='C:\\Program Files (x86)\\Dropbox\\Client\\193.4.5594\\python-packages.zip\\dropbox\\client\\ui\\common\\boot_error.pyc'
                      	not found
                parent	not found
TMP: C:\Users\larry\AppData\Local\Temp
TEMP: C:\Users\larry\AppData\Local\Temp
tempdir: 'C:\\Users\\larry\\AppData\\Local\\Temp'
         real_path='C:\\Users\\larry\\AppData\\Local\\Temp'
               	mode=0o40777	uid=0	gid=0
         parent	mode=0o40777	uid=0	gid=0
Traceback (most recent call last):
  File "desktop/dropbox/fs_api/lifecycle.py", line 235, in client
  File "desktop/dropbox/fs_api/lifecycle.py", line 283, in _create_thin_client
  File "desktop/dropbox/fs_api/fs_api_adapter.py", line 50, in __init__
  File "desktop\extensions\fs_api\fs_api_python.pyx", line 63, in fs_api_python.FsApiServer.__cinit__
fs_api_python.FsApiError: "Initializing fs api |>> Initializing application filesystem |>> Attempting to initialize dbx cache directory |>> NtSetBasicInformation syscall: new handle |>> ACCESS_DENIED |>> Permission denied"

The above exception was the direct cause of the following exception:

Traceback (most recent call last):
  File "desktop/dropbox/client/main.py", line 879, in wrapper
  File "desktop/dropbox/client/main.py", line 6729, in finish_dropbox_boot
  File "desktop/dropbox/client/message_queue.py", line 306, in _wrapped
  File "desktop/dropbox/client/main.py", line 6191, in _init_components_for_account
  File "desktop/dropbox/client/main.py", line 6114, in create_sync_engine
  File "desktop/dropbox/sync_engine_boundary/factory.py", line 225, in make_sync_engine
  File "desktop/dropbox/sync_engine/nucleus/classic_client/sync_engine.py", line 243, in __init__
  File "desktop/dropbox/sync_engine/nucleus/classic_client/modern_client/modern_client.py", line 285, in __init__
  File "desktop/dropbox/sync_engine/nucleus/classic_client/modern_client/base.py", line 242, in __init__
  File "../win32_x86_64_dropbox_virtual_env/python38/Lib/functools.py", line 967, in __get__
  File "desktop/dropbox/fs_api/lifecycle.py", line 259, in client
dropbox.fs_api.lifecycle.FsApiClientCreationException: "Initializing fs api |>> Initializing application filesystem |>> Attempting to initialize dbx cache directory |>> NtSetBasicInformation syscall: new handle |>> ACCESS_DENIED |>> Permission denied"